| 000 | 03517ntm a2200361 i 4500 | ||
|---|---|---|---|
| 001 | vtls000104330 | ||
| 003 | KUKTEM | ||
| 005 | 20251117113403.0 | ||
| 008 | 180718s2017 my a f a m 000 0 eng d | ||
| 020 | _aTHE0000863(Local) | ||
| 039 | 9 |
_a201905271628 _bnazirah _c201808131524 _dfateeha _y201807181623 _zfateeha |
|
| 040 |
_aUMP _beng _cUMP _erda |
||
| 090 | _aFKKSA .C438 2017 r Bc. | ||
| 100 | 1 |
_aChatterton, Charlene Cassandra, _eauthor. |
|
| 245 | 1 | 0 |
_aExtracting bioactive compounds from moringa oleifera leaves for anticancer product / _cCharlene Cassandra Chatterton |
| 264 | 1 |
_aKuantan, Pahang : _bUMP, _c2017 |
|
| 300 |
_axi, 41 pages : _billustrations (some color) ; _c30 cm. + _e1 CD ROM |
||
| 336 |
_atext _2rdacontent |
||
| 336 |
_atext _2rdacontent |
||
| 337 |
_aunmediated _2rdamedia |
||
| 337 |
_acomputer _2rdamedia |
||
| 338 |
_avolume _2rdacarrier |
||
| 338 |
_acomputer disc _2rdacarrier |
||
| 347 |
_atext file _bPDF _2rda |
||
| 500 | _aFaculty of Chemical & Natural Resources Engineering | ||
| 502 | _aProject Paper (Bachelors of Chemical Engineering) -- Universiti Malaysia Pahang – 2017 | ||
| 504 | _aIncludes bibliographical references | ||
| 520 | 3 | _aCancer is one of the most dangerous illness in the world. It occurs when cells in the body divide at an uncontrolled rate which then produces lumps or masses of tissue known as tumour. In addition, it affects the digestive, nervous and circulatory systems, these tumours also produce hormones which disrupts body functions. A benign tumour which remains in the same spot is harmless. On the contrary, a malignant tumour is dangerous as it may destroy healthy cells. These malignant tumours spread to healthy cells through the blood or lymphatic system. This condition is known as metastasis. Nowadays, various modern cancer treatments are available including surgery, drugs, chemotherapy, radiation therapy, steroid medications, and hormonal therapy. However, there are numerous side effects that arise from these modern treatments such as heart, lung, endocrine system, bone, joint, soft tissue, brain, spinal cord, nerve, memory, dental, vision and digestion problems. Moreover, the patient may suffer from emotional difficulties, fatigue as well as develop secondary type of cancer. In order to prevent side effects which arise from modern cancer treatments, a more natural approach with no detrimental effects to human health is required to combat cancer. The objectives of this research is to extract the bioactive compounds from the leaves of Moringa oleifera and to test the effect of the extracted material on cancer cells. In this study, the bioactive compounds from Moringa oleifera leaves is extracted using two methods which are the Soxhlet extraction method using ethanol, 2-propanol, acetone, petroleum ether and water solvent and the soaking method using ethanol and boiling water as solvent. Sample S2 which employed the Soxhlet extraction technique using water as the solvent exhibited significant cytotoxic activity against the human breast adenocarcinoma cancer cell line (MCF-7) in a concentration dependent manner with an IC50 value of 81.77±6.05g/mL. The other samples showed no cytotoxic activity. | |
| 610 | 2 | 0 |
_aFaculty of Chemical & Natural Resources Engineering _xDissertations |
| 650 | 0 |
_aUniversities and colleges _xDisertations |
|
| 650 | 0 | _aTheses | |
| 999 |
_aVIRTUA40 _c7782 _d7788 |
||
| 999 | _aVTLSSORT0080*0200*0400*0900*1000*2450*2640*3000*3360*3361*3370*3371*3380*3381*3470*5000*5020*5040*5200*6100*6500*6501*9992 | ||