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008 200217t20192019my a|||fr6m|| 000 0 eng d
020 _aTHE0008620(Local)
_qhardback
040 _aUMP
_beng
_cUMP
_erda
090 _aFTeK .A757 2019 r Bc.
100 0 _aSiti Nur Arisha Muhamad Zulkarnain,
_eauthor.
245 1 0 _aDevelopment and evaluation of centella asiatica powder by freeze drying :
_bcomparison of extraction methods on yield and hygroscopicity /
_cSiti Nur Arisha Muhamad Zulkarnain
264 1 _aKuantan, Pahang :
_bUMP,
_c2019
264 4 _c© 2019
300 _axii, 65 pages :
_billustrations (some color) ;
_c30 cm. +
_e1 CD-ROM
336 _atext
_2rdacontent
336 _atext
_2rdacontent
337 _aunmediated
_2rdamedia
337 _acomputer
_2rdamedia
338 _avolume
_2rdacarrier
338 _acomputer disc
_2rdacarrier
347 _atext file
_bPDF
_2rda
500 _aFaculty of Engineering Technology
502 _aProject Paper (Bachelor of Manufacturing Engineering Technology (Pharmaceutical)) -- Universiti Malaysia Pahang – 2019
504 _aIncludes bibliographical references
520 3 _aNovel techniques and the development of new methods has provided an opportunity to obtain highly purified natural bioactive compound extracts with potential for the treatment and prevention of various diseases. This research compares the percentage yield of Centella asiatica obtained through freeze drying that was aqueous-extracted earlier by conventional extraction method (decoction and infusion) and an advanced non-conventional extraction method; ultrasound-assisted extraction (UAE).The physical stability of the powder obtained was then tested by hygroscopicity test. The studies were conducted using gravimetric sorption analysis method with slight modification. Each of the powder samples was subjected to the pretreatment at 45 °C, 10% RH followed by equilibrating at 25 °C, 80% RH and individually categorized as per European Pharmacopeia. UAE generated the highest powder yield (11.65%) followed by infusion (10.48%) and decoction (10.03%). After 24 hours of hygroscopicity analysis, all three samples were found to be very hygroscopic since their respective percentage of water sorption was more than 15%. The highest percentage of water sorption was by decoction (71.31%), followed by infusion (71.28%) and lastly UAE (68.71%).
610 2 0 _aFaculty of Engineering Technology
_xDissertations
650 0 _aUniversities and Colleges
_xDissertations
650 0 _aTheses
942 _2lcc
_cPSM