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008 220405t20212021my a|||fram|| 001 0 eng d
020 _aTHE0009279(Local)
040 _aUMP
_beng
_cUMP
_erda
090 _aKK .L56 2021 r Thesis
100 1 _aLim Sheh Hong,
_eauthor.
245 1 0 _aComputational study of hemodynamics analysis between mri measurement and cfd simulation on segmented patient-specific cerebral aneurysm model /
_cLim Sheh Hong
264 1 _aKuantan, Pahang :
_bUMP,
_c2021
264 4 _aΒ© 2021
300 _axiii, 144 pages :
_billustrations (some color) ;
_c30 cm. +
_e1 CD ROM
336 _atext
_2rdacontent
337 _aunmediated
_2rdamedia
338 _avolume
_2rdacarrier
347 _atext file
_bPDF
_2rda
500 _aCollege of Engineering
502 _aThesis (Master of Science) -- Universiti Malaysia Pahang – 2021
504 _aIncludes bibliographical references
520 3 _aThe implementation of computational fluid dynamics (CFD) analysis was extensively performed to investigate the hemodynamics using segmented patient-specific cerebral aneurysm model geometry reconstructed from a medical image in this research. According to previous studies, the low-resolution magnetic resonance imaging (MRI) medical image produces a high measurement error and leads to inaccurate hemodynamics approximations with a large velocity difference of approximately 40 % between MRI measurement and CFD simulation. Besides, setting patient-specific boundary conditions before CFD analysis is critical, but there is no unified rule, especially for the setup of model geometry with bifurcation, which requires multiple outlet boundaries. Therefore, this study investigated the extracted model geometry with different threshold coefficients, πΆπ‘‘β„Žπ‘Ÿπ‘’π‘ , through image segmentation process on the patient-specific cerebral aneurysm and to evaluate the hemodynamics factors for cerebral aneurysms using digital subtraction angiography (DSA) and MRI medical images with the implementation of pressure fixed (P-fixed) approach as well as MRI measurement, which are the crucial elements in achieving the objectives. Moreover, the average relative error, Er,avg, upon steady-state simulation, was used to examine the trend of average velocity, Vavg, and maximum velocity, Vmax, between MRI measurement and CFD simulation. This study concluded that the cerebral aneurysm model geometry extraction with different threshold values has profound effects on physical and hemodynamics parameters. The optimised cerebral aneurysm model geometry was found at threshold coefficients, πΆπ‘‘β„Žπ‘Ÿπ‘’π‘ , ranging from 0.3 to 0.5. Nevertheless, high wall shear stress (WSS) distribution, pressure distribution, and velocity flow field are among the hemodynamics factors contributing to the cerebral aneurysm growing and rupturing. This study also found a velocity flow field difference with average relative error, Er,avg, of 11.6723 % and 37.3647 %, in terms of average velocity, Vavg, and maximum velocity, Vmax, respectively, between MRI measurement and CFD simulation through the P-fixed approach.
610 2 0 _aCollege of Engineering
_xDissertations
650 0 _aUniversities and colleges
_xDissertations
650 0 _aTheses
942 _2lcc
_cTHESIS