Investigating the role of complement c4 in human type 1 diabetes mellitus patients / (Record no. 103921)

MARC details
000 -LEADER
fixed length control field 02921ntm a2200337 i 4500
003 - CONTROL NUMBER IDENTIFIER
control field MY-KuUP
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20260123174840.0
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS
fixed length control field t||||fs|||| 000 0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field ta
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 260123t20252025my a|||fs|||| 000 0 eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number THE0010309 (Local)
Qualifying information Hardback
040 ## - CATALOGING SOURCE
Original cataloging agency UMPSA
Language of cataloging eng
Transcribing agency UMPSA
Description conventions rda
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) FIST .M38 2025 r Bc.
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Pui Ern, Mavis Wong,
Relator term author.
245 10 - TITLE STATEMENT
Title Investigating the role of complement c4 in human type 1 diabetes mellitus patients /
Statement of responsibility, etc. Mavis Wong Pui Er
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture Kuantan, Pahang :
Name of producer, publisher, distributor, manufacturer UMPSA,
Date of production, publication, distribution, manufacture, or copyright notice 2025
264 #4 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice © 2025
300 ## - PHYSICAL DESCRIPTION
Extent xiii, 86 pages :
Other physical details illustrations ;
336 ## - CONTENT TYPE
Source rdacontent
Content type term text
337 ## - MEDIA TYPE
Source rdamedia
Media type term unmediated
338 ## - CARRIER TYPE
Source rdacarrier
Carrier type term volume
347 ## - DIGITAL FILE CHARACTERISTICS
Source rda
File type text file
Encoding format PDF
500 ## - GENERAL NOTE
General note Faculty of Industrial Sciences and Technology
502 ## - DISSERTATION NOTE
Dissertation note Final Year Report (Bachelor of Applied Science in Industrial Biotechnology) -- Universiti Malaysia Pahang Al-Sultan Abdullah - 2025
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc. note Include bibliographical reference
520 3# - SUMMARY, ETC.
Summary, etc. The complement system is a crucial part of the immune system; it consists of a series of proteins that work together to defend the body against infections. Complement proteins C4 and C4a have been linked to T1DM due to their role in immune response and defence systems. Since no research has been done on the subject in T1DM patients from Malaysia, further investigation is necessary to fully comprehend the potential importance of complement proteins and the role of complement proteins in T1DM. The goal of this study is to investigate the complement concentration using the enzymelinked immunosorbent assay (ELISA) technique, determine the concentration of serum complement C4 and C4a patients with T1DM in Malaysia compared to healthy controls, and investigate the connection between complement protein C4 and C4a with other clinical parameters such as age, gender, and the duration since the disease has been present. To achieve the goals, 9 T1DM patients who met the diagnosis criteria were enlisted, and the blood sample was collected. ELISA is an enzyme-linked immunosorbent assay technique widely used to identify and measure peptides, proteins, antibodies, and hormones. This research uses sandwich ELISA to determine complement protein C4 and C4a concentrations. Based on the findings, we can conclude that the C4 and C4a concentrations do not exhibit significant variation across ethnicities, age groups, and genders within the Malaysian T1DM patient and healthy control. Increasing the sample size may be necessary to improve this experiment's outcomes. A larger sample size enhances the statistical power of the analysis, making it easier to identify significant
610 20 - SUBJECT ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element Faculty of Industrial Sciences and Technology
General subdivision Dissertations
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Universities and colleges
General subdivision Dissertations
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Final Year Report
General subdivision Dissertations
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Library of Congress Classification
Koha item type Restricted Collection
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
  Not lost Library of Congress Classification     UMPLIB GAMBANG UMPLIB GAMBANG 23/01/2026   FIST .M38 2025 r Bc. T000003688 23/01/2026 23/01/2026 Restricted Collection

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