Application of deep eutectic solvent as a green solvent in extracting of phytochemicals compound in phyllanthus niruri / (Record no. 104762)

MARC details
000 -LEADER
fixed length control field 04156ntm a2200349 i 4500
003 - CONTROL NUMBER IDENTIFIER
control field MY-KuUP
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20260421120706.0
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS
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007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
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008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 260421t20252025my a|||fr|||| 000 0 eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number THE0010484 (Local)
Qualifying information Hardback
040 ## - CATALOGING SOURCE
Original cataloging agency UMPSA
Language of cataloging eng
Transcribing agency UMPSA
Description conventions rda
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) FIST .P85 2025 r Bc.
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Sabrina Liew, Pui Yee,
Relator term author.
245 10 - TITLE STATEMENT
Title Application of deep eutectic solvent as a green solvent in extracting of phytochemicals compound in phyllanthus niruri /
Statement of responsibility, etc. Sabrina Liew Pui Yee
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture Kuantan, Pahang :
Name of producer, publisher, distributor, manufacturer UMPSA,
Date of production, publication, distribution, manufacture, or copyright notice 2025
264 #4 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice © 2025
300 ## - PHYSICAL DESCRIPTION
Extent xiii , 87 pages :
Other physical details illustrations ;
336 ## - CONTENT TYPE
Source rdacontent
Content type term text
337 ## - MEDIA TYPE
Source rdamedia
Media type term unmediated
338 ## - CARRIER TYPE
Source rdacarrier
Carrier type term volume
347 ## - DIGITAL FILE CHARACTERISTICS
Source rda
File type text file
Encoding format PDF
500 ## - GENERAL NOTE
General note Faculty of Industrial Sciences and Technology
502 ## - DISSERTATION NOTE
Dissertation note Final Year Report (Bachelor of Applied Science of Industrial Chemistry) -- Universiti Malaysia Pahang Al-Sultan Abdullah - 2025
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc. note Include bibliographical reference
520 3# - SUMMARY, ETC.
Summary, etc. A study was performed to extract Phyllanthus Niruri (aerial part of leaves) by using Ultrasound-assisted Extraction (UAE) and Natural Deep Eutectic Solvent (NaDES) as extraction solvent and to analyze phytochemical compounds found in the extract using High Performance Liquid Chromatography (HPLC) and Gas Chromatography-Mass Spectrometry (GC-MS). NaDES were synthesized by combinations of hydrogen bond acceptor (HBA): Choline chloride and hydrogen bond donors (HBD): Lactic acid, Oxalic acid, Citric acid (II) monohydrate, L(+)-Ascorbic acid and L-(+)-Tartaric acid. Both were stirred in water bath at 80 ºC until a homogenous liquid was formed. FTIR-ATR and KBr were used to perform analysis of liquid (wavelength 700 and 4000 ��������−1 ) and solid sample (400 and 4000 ��������−1) respectively. Phyllanthus Niruri was cleaned, dried in oven and powdered in preparation of extraction. UAE was conducted for 30 minutes at 60 °C and 200 W using an ultrasonic (Branson ®) machine where 10 mL of NaDES solvent was used to extract 1.0 g of precisely weighed dry herb powder. HPLC and GC-MS analysis was conducted for qualitative and quantitative research of the NaDES extract. Results depicted the NADES-1 was the fastest to form homogenous liquid (10 min) slowest, NADES-4 (5 hr) Density of NaDES were also calculated and arranged in descending order, (NADES-3 > NADES-5 > NADES-4 > NADES-2 > NADES-1). Besides, in FTIR analysis demonstrated the characteristics wavelength of IR for synthesized NADES according to O-H Stretching, C-H Stretching, C=O Stretching, N-H Bending and C-O Stretching. The bond shifting of C=O and -OH of FTIR analysis in range of 1650-1750 ��������−1 and 3200–3500 ��������−1 demonstrated that every NADES was successfully prepared. UAE showed deeper colour of extracts upon complete extraction. HPLC analysis of extracts found potential compounds: Phyllanthin, hypophyllanthin and niranthin when referred to previous studies. Finally, in GC-MS analysis, NADES-2 extracts demonstrated highest abundance achieved by butanedioic acid, 2,3-dihydroxy-, dimethyl ester. Limited studies showed this compound is a naturally occurring compound. Thus, benzene, 4-ethyl-1,2-dimethoxy- from analysis of NADES-5 was selected as the most outperform analysis as this compound is widely found in plant extracts. These findings gained extra information in identification of new phytochemical compounds that has yet been explored in analysis of Phyllanthus Niruri as compared to previous studies. However, more approach has to be conducted in verification of the new compounds observe. In short, application of deep eutectic solvents in extracting phytochemical compounds found in Phyllanthus Niruri is achievable.
610 20 - SUBJECT ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element Faculty of Industrial Sciences and Technology
General subdivision Dissertations
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Universities and colleges
General subdivision Dissertations
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Theses
General subdivision Dissertations
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier https://umpir.ump.edu.my/id/eprint/46125
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Library of Congress Classification
Koha item type Final Year Report
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
  Not lost Library of Congress Classification     UMPLIB GAMBANG UMPLIB GAMBANG 21/04/2026   FIST .P85 2025 r Bc. T0000033756 21/04/2026 21/04/2026 Final Year Report

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