Fabrication and characterisation of drug-loaded pla-starch-ncc nanofibers via electrospinning for biomedical applications / (Record no. 105211)

MARC details
000 -LEADER
fixed length control field 03036ntm a2200349 i 4500
003 - CONTROL NUMBER IDENTIFIER
control field MY-KuUP
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20260714144436.0
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS
fixed length control field t|||||r|||| 000 0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field ta
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 260714t20252025my a|||fr|||| 000 0 eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number THE0010725 (Local)
Qualifying information Hardback
040 ## - CATALOGING SOURCE
Original cataloging agency UMPSA
Language of cataloging eng
Transcribing agency UMPSA
Description conventions rda
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) FTKKP .A558 2025 r Bc.
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Anith Afiqah Nur ‘izzatul Binti Mohamad Saadun, , ,
Relator term author.
245 10 - TITLE STATEMENT
Title Fabrication and characterisation of drug-loaded pla-starch-ncc nanofibers via electrospinning for biomedical applications /
Statement of responsibility, etc. Anith Afiqah Nur ‘izzatul Binti Mohamad Saadun
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture Kuantan, Pahang :
Name of producer, publisher, distributor, manufacturer UMPSA,
Date of production, publication, distribution, manufacture, or copyright notice 2025
264 #4 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice © 2025
300 ## - PHYSICAL DESCRIPTION
Extent xi, 32 pages :
Other physical details illustrations ;
336 ## - CONTENT TYPE
Source rdacontent
Content type term text
337 ## - MEDIA TYPE
Source rdamedia
Media type term unmediated
338 ## - CARRIER TYPE
Source rdacarrier
Carrier type term volume
347 ## - DIGITAL FILE CHARACTERISTICS
Source rda
File type text file
Encoding format PDF
500 ## - GENERAL NOTE
General note Faculty of Chemical and Process Engineering Technology
502 ## - DISSERTATION NOTE
Dissertation note Final Year Report (Bachelor of Manufacturing Engineering Technology (Pharmaceuticals) with Hons ) -- Universiti Malaysia Pahang Al-Sultan Abdullah - 2025
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc. note Include bibliographical reference
520 3# - SUMMARY, ETC.
Summary, etc. Transdermal drug delivery system (TDDS) has been increasingly focused on achieving greater precision and accuracy at the target site compared to traditional methods. Biopolymer nanofibers are promising for drug delivery systems (DDS) due to their biodegradability, high surface area, and biocompatibility. This study focuses on the fabrication and characterization of nanofibers composed of polylactic acid (PLA), starch, and nanocrystalline cellulose (NCC) with varying concentrations (1 wt%, 3 wt%, and 5 wt%) for biomedical applications. PLA is widely utilised due to its biodegradability and biocompatibility, but its inherent brittleness and hydrophobic nature limit its mechanical performance and water adsorption capacity. To address these limitations, starch was incorporated to enhance hydrophilicity, while NCC was added to reinforce mechanical strength and stability. The nanofibers were fabricated using the needleless electrospinning technique and the morphological, chemical, and mechanical properties of the nanofibers were analysed using scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FTIR), swelling behaviour, and weight loss analysis. Among the tested formulations, nanofibers with 3 wt% NCC exhibited the larger fiber diameter, swelling resistance, and structural integrity, mitigating PLA’s hydrophobic limitations while maintaining optimal performance. These findings highlight the potential of PLA-starch-NCC nanofibers, particularly at 3 wt% NCC, in developing sustainable and high-performance biomaterials for advanced drug delivery systems.
610 20 - SUBJECT ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element Faculty of Chemical and Process Engineering Technology
General subdivision Dissertations
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Universities and colleges
General subdivision Dissertations
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Theses
General subdivision Dissertations
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier https://umpir.ump.edu.my/id/eprint/45608
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Library of Congress Classification
Koha item type Final Year Report
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
  Not lost Library of Congress Classification     UMPLIB GAMBANG UMPLIB GAMBANG 14/07/2026   FTKKP .A558 2025 r Bc. T000004318 14/07/2026 14/07/2026 Final Year Report

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