Exploring stirrer variations in enhancing carbamazepine saccharin cocrystals properties / (Record no. 105296)

MARC details
000 -LEADER
fixed length control field 02921ntm a2200349 i 4500
003 - CONTROL NUMBER IDENTIFIER
control field MY-KuUP
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20260724121033.0
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS
fixed length control field t|||||r|||| 000 0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field ta
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 260724t20252025my a|||fr|||| 000 0 eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number THE0010754 (Local)
Qualifying information Hardback
040 ## - CATALOGING SOURCE
Original cataloging agency UMPSA
Language of cataloging eng
Transcribing agency UMPSA
Description conventions rda
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) FTKKP .H53 2025 r Bc.
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Nurul Hidayah Binti Mohd Zaini, , ,
Relator term author.
245 10 - TITLE STATEMENT
Title Exploring stirrer variations in enhancing carbamazepine saccharin cocrystals properties /
Statement of responsibility, etc. Nurul Hidayah Binti Mohd Zaini
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture Kuantan, Pahang :
Name of producer, publisher, distributor, manufacturer UMPSA,
Date of production, publication, distribution, manufacture, or copyright notice 2025
264 #4 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice © 2025
300 ## - PHYSICAL DESCRIPTION
Extent 34 pages :
Other physical details illustrations ;
336 ## - CONTENT TYPE
Source rdacontent
Content type term text
337 ## - MEDIA TYPE
Source rdamedia
Media type term unmediated
338 ## - CARRIER TYPE
Source rdacarrier
Carrier type term volume
347 ## - DIGITAL FILE CHARACTERISTICS
Source rda
File type text file
Encoding format PDF
500 ## - GENERAL NOTE
General note Faculty of Chemical and Process Engineering Technology
502 ## - DISSERTATION NOTE
Dissertation note Final Year Report (Bachelor of Manufacturing Engineering Technology (Pharmaceuticals) with Hons ) -- Universiti Malaysia Pahang Al-Sultan Abdullah - 2025
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc. note Include bibliographical reference
520 3# - SUMMARY, ETC.
Summary, etc. Cocrystallization improves drug solubility by connecting hydrogen bonds between the active pharmaceutical ingredients and the coformer. Carbamazepine (CBZ) with solubility problems have been studied with saccharin (SAC) to form cocrystal using cooling crystallization method. Mixing is the main process in cooling crystallization to achieve the desired cocrystal, however the research of the stirrer properties is limited. In this study, different types of stirrer which are turbine, paddle and straight stirrers were used to investigate the impact on the cocrystals. The 1:1 ratio of CBZ:SAC was mixed with ethanol in the crystallizer and cooling crystallization was performed for four cycles. After the fourth cycle, the cocrystals were collected and dried for 24 hours. The characterizations testing were conducted using X-ray Diffraction (XRD), Fourier-transform Infrared Spectroscopy (FTIR) and imaging inverted microscopy. Based on crystallization temperature obtained, the straight stirrer formed the cocrystal fastest while the turbine stirrer formed the cocrystal slowest. The FTIR and XRD analysis revealed that all types of stirrer used successfully formed the carbamazepine saccharin cocrystals, while morphology analysis shows that all the cocrystals behave plate-like shape with different sizes. It was concluded that different types of the stirrer used significantly influenced the crystallization temperature and the size of the cocrystal produced highlighting the importance of stirrer selection to produce cocrystal with desired properties.
610 20 - SUBJECT ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element Faculty of Chemical and Process Engineering Technology
General subdivision Dissertations
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Universities and colleges
General subdivision Dissertations
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Theses
General subdivision Dissertations
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier https://umpir.ump.edu.my/id/eprint/47666
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Library of Congress Classification
Koha item type Final Year Report
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
  Not lost Library of Congress Classification     UMPLIB GAMBANG UMPLIB GAMBANG 24/07/2026   FTKKP .H53 2025 r Bc. T000004348 24/07/2026 24/07/2026 Final Year Report

Perpustakaan Universiti Malaysia Pahang Al-Sultan Abdullah
26600 Pekan, Pahang Darul Makmur
Phone: +609 431 5063 (Gambang) / +609 431 5035 (Pekan)
Email: umplibrary@umpsa.edu.my

Connect With Us