Formulation of quercetin tablets: enhancing solubility with polysorbate 20 / (Record no. 105299)

MARC details
000 -LEADER
fixed length control field 02802ntm a2200349 i 4500
003 - CONTROL NUMBER IDENTIFIER
control field MY-KuUP
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20260724154558.0
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS
fixed length control field t|||||r|||| 000 0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field ta
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 260724t20252025my a|||fr|||| 000 0 eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number THE0010757 (Local)
Qualifying information Hardback
040 ## - CATALOGING SOURCE
Original cataloging agency UMPSA
Language of cataloging eng
Transcribing agency UMPSA
Description conventions rda
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) FTKKP .R33 2025 r Bc.
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Rabiatul Adawiyah Binti Mohd Adnan, , ,
Relator term author.
245 10 - TITLE STATEMENT
Title Formulation of quercetin tablets: enhancing solubility with polysorbate 20 /
Statement of responsibility, etc. Rabiatul Adawiyah Binti Mohd Adnan
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture Kuantan, Pahang :
Name of producer, publisher, distributor, manufacturer UMPSA,
Date of production, publication, distribution, manufacture, or copyright notice 2025
264 #4 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice © 2025
300 ## - PHYSICAL DESCRIPTION
Extent xi, 57 pages :
Other physical details illustrations ;
336 ## - CONTENT TYPE
Source rdacontent
Content type term text
337 ## - MEDIA TYPE
Source rdamedia
Media type term unmediated
338 ## - CARRIER TYPE
Source rdacarrier
Carrier type term volume
347 ## - DIGITAL FILE CHARACTERISTICS
Source rda
File type text file
Encoding format PDF
500 ## - GENERAL NOTE
General note Faculty of Chemical and Process Engineering Technology
502 ## - DISSERTATION NOTE
Dissertation note Final Year Report (Bachelor of Manufacturing Engineering Technology (Pharmaceuticals) with Hons ) -- Universiti Malaysia Pahang Al-Sultan Abdullah - 2025
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc. note Include bibliographical reference
520 3# - SUMMARY, ETC.
Summary, etc. Quercetin is a bioactive flavonoid present in different types of plant products, which is famous for antioxidative, anti-inflammatory, and therapeutic actions. However, due to its insolubility in water and very poor bioavailability, its effectiveness as an oral health supplement remains very low. The purpose of this study is to formulate and characterize a quercetin tablet formulation employing polysorbate 20 as a solubility-enhancing excipient. The objectives include determining the solubility, dissolution rate, and physical properties of quercetin tablets following the impact of using varying concentrations of polysorbate 20 at concentrations of 2%, 2.75%, 3.5%, 4.25%, and 5%. The technique includes wet granulation to obtain granules and tablet compression through a single-punch tablet press. Tablet friability, hardness, disintegration, and dissolution tests are performed to check the quality and efficacy of the tablets which are in conformities to USP standards. The focus of this research is to overcome the solubility issues associated with quercetin by formulating a higher-yielding method that improves its pharmacological value. Finally, the best composition of polysorbate 20 for formulation of quercetin tablets was 14% of polysorbate 20. In conclusion, this study provides knowledge in the enhancement of oral drug delivery systems of poorly soluble compounds for better therapeutic outcomes and patient compliance.
610 20 - SUBJECT ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element Faculty of Chemical and Process Engineering Technology
General subdivision Dissertations
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Universities and colleges
General subdivision Dissertations
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Theses
General subdivision Dissertations
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier https://umpir.ump.edu.my/id/eprint/47715
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Library of Congress Classification
Koha item type Final Year Report
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Permanent Location Current Location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
  Not lost Library of Congress Classification     UMPLIB GAMBANG UMPLIB GAMBANG 24/07/2026   FTKKP .R33 2025 r Bc. T000004351 24/07/2026 24/07/2026 Final Year Report

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