MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03420nam a2200325 a 4500 |
| 001 - CONTROL NUMBER |
|---|
| control field |
vtls000046766 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
KUKTEM |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20251117150453.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
100630t2010 njuaf f b 001 0 eng |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9780470281741 (cloth) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
047028174X (cloth) |
| 039 #9 - LEVEL OF BIBLIOGRAPHIC CONTROL AND CODING DETAIL [OBSOLETE] |
|---|
| Level of rules in bibliographic description |
201107132358 |
| Level of effort used to assign nonsubject heading access points |
VLOAD |
| Level of effort used to assign subject headings |
201011221624 |
| Level of effort used to assign classification |
fauzi |
| Level of effort used to assign subject headings |
201011221623 |
| Level of effort used to assign classification |
fauzi |
| -- |
201006301439 |
| -- |
faiz |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
UMP |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
|---|
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
QP601.5 .E58 2010 |
| 245 00 - TITLE STATEMENT |
|---|
| Title |
Enzyme inhibition in drug discovery and development : |
| Remainder of title |
the good and the bad / |
| Statement of responsibility, etc. |
edited by Chuang Lu, Albert P. Li |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
|---|
| Place of publication, distribution, etc. |
Hoboken, N.J. : |
| Name of publisher, distributor, etc. |
Wiley, |
| Date of publication, distribution, etc. |
c2010 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
xiii, 854 p., [8] p. of plates : |
| Other physical details |
ill. (some col.) ; |
| Dimensions |
25 cm. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
|---|
| Bibliography, etc. note |
Includes bibliographical references and index |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
The drug discovery process / Gerald T. Miwa -- Medicinal chemistry of the optimization of enzyme inhibitors / Geraldine Harriman, Amy Elder, and Indranath Ghosh -- Bioanalytical technologies in drug discovery / Jing-Tao Wu -- Safety biomarkers in drug development : emerging trends and implications / Eric R. Fedyk -- The role of drug metabolism in drug discovery / Tonika Bohnert and Liang-Shang Gan -- Applied pharmacokinetics in drug discovery and development / Hua Yang ... [et al.] -- Enzyme inhibition and inactivation : cytochrome P450 enzymes / R. Scott Obach -- Cytochrome P450 induction / Edward L. LeCluyse ... [et al.] -- Inhibition of drug-metabolizing enzymes in gastrointestinal tract and its influence on the drug-drug interaction prediction / Aleksandra Galetin and J. Brian Houston -- Enzyme inhibition in various in vitro systems / Ping Zhao -- Cytochrome P450 degradation and its clinical relevance / Mingxiang Liao ... [et al.] -- Complexities of working with UDP-glucuronosyltransferases (UGTs) : focus on enzyme inhibition / Michael B. Fisher -- |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Evaluation of inhibitors of drug metabolism in human hepatocytes / Albert P. Li and Chuang Lu -- Grapefruit juice and its constituents as new esterase inhibitors / Suresh K. Balani -- Transporter-xenobiotic interactions : an important aspect of drug development studies / Gang Luo, Richard Ridgewell, and Thomas Guenthner -- Polymorphisms of drug transporters and their clinical implications / Cindy Q. Xia and Johnny J. Yang -- Clinical drug interactions due to metabolic inhibition : prediction, assessment, and interpretation / Lisa L. von Moltke and David J. Greenblatt -- Predicting interindividual variability of metabolic drug-drug interactions : identifying the causes and accounting for them using a systems approach / Amin Rostami-Hodjegan -- NF-kB : mechanism, tumor biology, and inhibitors / Lenny Dang -- G-protein-coupled receptors as drug targets / Wenyan Miao and Lijun Wu -- Pharmacological modulation of ion channels for the treatment of chronic pain / Yi Liu and Ning Qin -- Targeting the mTOR pathway for tumor therapeutics / Wei Chen -- HIV-1 protease inhibitors as antiretroviral agents / Sergei V. Gulnik, Elena Afonina, and Michael Eissenstat |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Enzyme inhibitors |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Drug development |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Drugs |
| General subdivision |
Metabolism |
| 650 12 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Enzyme Inhibitors |
| General subdivision |
pharmacology |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Drug Discovery |
| General subdivision |
methods |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Enzyme Inhibitors |
| General subdivision |
chemical synthesis |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Lu, Chuang |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Li, A. P. |